https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51348 Wed 28 Feb 2024 15:50:49 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51135 Wed 28 Feb 2024 15:41:51 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45255 Wed 26 Oct 2022 15:34:30 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45237 Wed 26 Oct 2022 15:07:16 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45180 Wed 26 Oct 2022 14:26:21 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45105 Wed 26 Oct 2022 13:21:01 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45130 Wed 26 Oct 2022 12:58:32 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:44987 Staphylococcus aureus, Escherichia coli, Enterococcus faecium, Klebsiella pneumoniae, Enterobacter sp and Acinetobacter baumannii) compared with standard of care or routine microbiology testing. Primary and secondary outcomes Expected hospital costs, counts of patient infections and colonisations, and deaths from bloodstream infections. Results In 2021, 97 539 patients in Queensland are expected to be infected or colonised with one of six multidrug-resistant organisms with standard of care testing. WGS surveillance strategy and earlier infection control measures could avoid 36 726 infected or colonised patients and avoid 650 deaths. The total cost under standard of care was $A170.8 million in 2021. WGS surveillance costs an additional $A26.8 million but was offset by fewer costs for cleaning, nursing, personal protective equipment, shorter hospital stays and antimicrobials to produce an overall cost savings of $30.9 million in 2021. Sensitivity analyses showed cost savings remained when input values were varied at 95% confidence limits. Conclusions Compared with standard of care, WGS surveillance at a state-wide level could prevent a substantial number of hospital patients infected with multidrug-resistant organisms and related deaths and save healthcare costs. Primary prevention through routine use of WGS is an investment priority for the control of serious hospital-associated infections.]]> Wed 26 Oct 2022 09:07:36 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:37320 Wed 24 Nov 2021 15:51:12 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30530 Wed 22 Aug 2018 18:00:28 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:32650 Wed 19 Jan 2022 15:18:54 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:24196 Wed 18 Aug 2021 08:22:06 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:52293 Wed 17 Apr 2024 14:31:51 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29929 FEver, hyperglycaemia (Sugar) and Swallowing (the FeSS protocols) in stroke, previously demonstrated in the Quality in Acute Stroke Care (QASC) trial to decrease 90-day death and dependency, into all stroke services in New South Wales (NSW), Australia's most populous state. Design: Pre-test/post-test prospective study. Setting: 36 NSW stroke services. Methods: Our clinical translational initiative, the QASC Implementation Project (QASCIP), targeted stroke services to embed 3 nurse-led clinical protocols (the FeSS protocols) into routine practice. Clinical champions attended a 1-day multidisciplinary training workshop and received standardised educational resources and ongoing support. Using the National Stroke Foundation audit collection tool and processes, patient data from retrospective medical record self-reported audits for 40 consecutive patients with stroke per site pre-QASCIP (1 July 2012 to 31 December 2012) were compared with prospective self-reported data from 40 consecutive patients with stroke per site post-QASCIP (1 November 2013 to 28 February 2014). Inter-rater reliability was substantial for 10 of 12 variables. Primary outcome measures: Proportion of patients receiving care according to the FeSS protocols pre-QASCIP to post-QASCIP. Results: All 36 (100%) NSW stroke services participated, nominating 100 site champions who attended our educational workshops. The time from start of intervention to completion of post-QASCIP data collection was 8 months. All (n=36, 100%) sites provided medical record audit data for 2144 patients (n=1062 pre-QASCIP; n=1082 post-QASCIP). Pre-QASCIP to post-QASCIP, proportions of patients receiving the 3 targeted clinical behaviours increased significantly: management of fever (pre: 69%; post: 78%; p=0.003), hyperglycaemia (pre: 23%; post: 34%; p=0.0085) and swallowing (pre: 42%; post: 51%; p=0.033). Conclusions: We obtained unprecedented statewide scale-up and spread to all NSW stroke services of a nurse-led intervention previously proven to improve long-term patient outcomes. As clinical leaders search for strategies to improve quality of care, our initiative is replicable and feasible in other acute care settings.]]> Wed 15 Dec 2021 16:10:19 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:43181 40 000 participants. Included studies consistently reported an increased risk associated with greater numbers of intraindividual risk factors or unhealthy behaviours and the opposite for healthy or protective behaviours. A meta-analysis of studies with dementia outcomes resulted in a pooled relative risk for dementia of 1.20 (95% CI 1.04 to 1.39) for one risk factor, 1.65 (95% CI 1.40 to 1.94) for two and 2.21 (95% CI 1.78 to 2.73) for three or more, relative to no risk factors. Limitations include dependence on published results and variations in study outcome, cognitive assessment, length of follow-up and definition of risk factor exposure. Conclusions The strength of the reported associations, the consistency across studies and the suggestion of a dose response supports a need to keep modifiable risk factor exposure to a minimum and to avoid exposure to additional modifiable risks. Further research is needed to establish whether particular combinations of risk factors confer greater risk than others.]]> Wed 14 Sep 2022 08:23:22 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45779 Wed 13 Mar 2024 08:57:16 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:36126 Wed 12 Feb 2020 16:22:06 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:36125 Wed 12 Feb 2020 16:01:07 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:47269 Wed 11 Jan 2023 10:20:43 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:26096 Wed 11 Apr 2018 16:27:54 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:20993 Wed 11 Apr 2018 15:59:54 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:24528 Wed 11 Apr 2018 15:24:21 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:19459 Wed 11 Apr 2018 15:12:47 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:15734 Wed 11 Apr 2018 15:04:13 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:15733 Wed 11 Apr 2018 14:55:40 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:11806 Wed 11 Apr 2018 14:52:14 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:18673 Wed 11 Apr 2018 14:31:33 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29131 Wed 11 Apr 2018 14:18:48 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:22667 Wed 11 Apr 2018 14:18:05 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:22634 Wed 11 Apr 2018 13:56:06 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:15731 Wed 11 Apr 2018 13:29:25 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30053 Wed 11 Apr 2018 13:04:34 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:25469 Wed 11 Apr 2018 13:00:02 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:21012 60 Gy) with curative intent, will be recruited from radiotherapy departments at 5 Australian sites. Assessments will be conducted at 4 time points (first and final week of radiotherapy, 4 and 12 weeks postradiotherapy). The primary outcome will be a nutritional status assessment. ETHICS AND DISSEMINATION: Ethics approval from all relevant bodies has been granted. Study findings will be disseminated widely through peer-reviewed publications and conference presentations.]]> Wed 11 Apr 2018 12:47:57 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30896 Wed 11 Apr 2018 12:43:29 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:21261 Wed 11 Apr 2018 12:22:40 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:22650 Wed 11 Apr 2018 11:14:14 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:26162 Wed 11 Apr 2018 11:01:03 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:24174 Wed 11 Apr 2018 10:48:24 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:24175 Wed 11 Apr 2018 10:40:14 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:15598 Wed 11 Apr 2018 10:37:55 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:24770 Wed 11 Apr 2018 10:37:18 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:25128 Wed 11 Apr 2018 10:21:32 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:24202 Wed 11 Apr 2018 09:54:59 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29465 Wed 11 Apr 2018 09:50:14 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:15729 Wed 11 Apr 2018 09:44:30 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:29399 Wed 10 Jul 2019 15:16:59 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:42925 Wed 07 Sep 2022 13:31:25 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:43060 Wed 07 Feb 2024 14:49:09 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33617 Wed 04 Sep 2019 09:39:14 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30534 Wed 02 Oct 2019 10:31:34 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:36339 Wed 01 Apr 2020 12:01:39 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:36725 Tue 30 Aug 2022 12:10:47 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:36224 Tue 30 Aug 2022 09:32:34 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51269 Tue 29 Aug 2023 15:41:29 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:31043 Tue 24 Jul 2018 10:12:36 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:39051 Tue 21 Mar 2023 17:43:57 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27763 Tue 19 Jun 2018 12:29:06 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:55144 Tue 16 Apr 2024 09:45:40 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:43062 Tue 13 Sep 2022 08:32:19 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:34415 Tue 03 Sep 2019 18:11:31 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33661 Tue 03 Sep 2019 18:01:29 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38102 Tue 03 Aug 2021 19:06:52 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:41347 Tue 02 Aug 2022 11:22:19 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:41324 Tue 02 Aug 2022 09:01:32 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:41327 Tue 02 Aug 2022 08:55:17 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30986 Tue 01 May 2018 09:16:11 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30923 Tue 01 May 2018 08:49:58 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:26546 Thu 31 May 2018 11:47:54 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45230 Thu 27 Oct 2022 12:26:23 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:36136 Thu 21 Oct 2021 12:52:43 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:25031 Thu 17 Feb 2022 09:30:04 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:36434 4 lobes), normal (2-4 lobes) and banded (1 lobe) neutrophils and enumerated. Results: Neutrophils from each subset were identified in all participants. Numbers of hypersegmented neutrophils were elevated in participants with airway disease compared with healthy controls (p<0.001). Both the number and the proportion of hypersegmented neutrophils were highest in COPD participants (median (Q1-Q3) of 1073.6 (258.8-2742) x 10 2/mL and 24.5 (14.0-46.5)%, respectively). An increased proportion of hypersegmented neutrophils in airway disease participants was significantly associated with lower forced expiratory volume in 1 s/forced vital capacity per cent (Spearman's r=-0.322, p=0.004). Conclusion: Neutrophil heterogeneity is common in BL and is associated with more severe airflow obstruction in adults with airway disease. Further work is required to elucidate the functional consequences of hypersegmented neutrophils in the pathogenesis of disease.]]> Thu 13 Jan 2022 10:29:04 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:24735 Thu 12 Apr 2018 09:00:48 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:40311 Thu 07 Jul 2022 17:03:37 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:41464 Thu 04 Aug 2022 11:26:19 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:41454 Thu 04 Aug 2022 10:23:29 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:24229 Thu 03 Feb 2022 12:20:32 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51410 Thu 02 May 2024 14:49:45 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:35625 Thu 02 Apr 2020 12:29:22 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38392 Mon 29 Jan 2024 17:47:33 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51235 Mon 28 Aug 2023 12:19:57 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:48682 Mon 27 Mar 2023 14:46:42 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51980 Mon 25 Sep 2023 12:09:03 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:52698 Mon 23 Oct 2023 14:05:48 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:18663 Mon 20 Jul 2015 17:06:14 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:18636 Mon 20 Jul 2015 16:45:12 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:35059 Mon 17 Jun 2019 11:20:45 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:24424 Mon 13 Jul 2020 13:33:18 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:44219 Mon 10 Oct 2022 16:59:44 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:42851 Mon 05 Sep 2022 15:40:20 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:35027 9 g/day. Results: Median daily sodium excretion was equivalent to 6.3 g salt/day (range 1–43 g/day); 35% had urinary sodium excretion values within the desirable range (<5 g salt/day), 37% had high values (5–9 g salt/day) and 28% had very high values (>9 g salt/day). Median UIC was 130 µg/L (IQR=58–202), indicating population iodine sufficiency (≥100 µg/L). Both UIC and UIE differed across salt intake categories (p<0.001) and were positively correlated with estimated salt intake (r=0.166 and 0.552, respectively; both p<0.001). Participants with salt intakes of <5 g/day were not meeting the Estimated Average Requirement for iodine intake (95 µg/day). Conclusions: In a nationally representative sample of South African adults, the association between indicators of population iodine status (UIC and UIE) and salt intake, estimated using 24-hour urinary sodium excretion, indicate that low salt intakes may compromise adequacy of iodine intakes in a country with mandatory iodisation of table salt. The iodine status of populations undergoing salt reduction strategies needs to be closely monitored to prevent re-emergence of iodine deficiency.]]> Mon 03 Jun 2019 14:03:50 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:41319 Mon 01 Aug 2022 14:15:27 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:51884 Fri 22 Sep 2023 09:08:56 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:38686 Fri 19 Aug 2022 10:18:15 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:42176 Fri 19 Aug 2022 09:36:34 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:53184 18 years) with or without a history of LBP recruited in April 2019 with quotas for country, age and gender. Primary and secondary outcome measures: Self-reported understanding of 14 terms (annular fissure, disc bulge, disc degeneration, disc extrusion, disc height loss, disc protrusion, disc signal loss, facet joint degeneration, high intensity zone, mild canal stenosis, Modic changes, nerve root contact, spondylolisthesis and spondylosis) commonly found in lumbar spine imaging reports. For each term, we also elicited worry about its seriousness, and whether its presence would indicate pain persistence and prompt fear of movement. Results: From 774 responses, we included 677 (87.5%) with complete and valid responses. 577 (85%) participants had a current or past history of LBP of whom 251 (44%) had received lumbar spine imaging. Self-reported understanding of all terms was poor. At best, 235 (35%) reported understanding the term € disc degeneration', while only 71 (10.5%) reported understanding the term € Modic changes'. For all terms, a moderate to large proportion of participants (range 59%-71%), considered they indicated a serious back problem, that pain might persist (range 52%-71%) and they would be fearful of movement (range 42%-57%). Conclusion: Common and usually non-serious terms in lumbar spine imaging reports are poorly understood by the general population and may contribute to the burden of LBP. Trial registration number: ACTRN12619000545167.]]> Fri 17 Nov 2023 11:26:17 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:36137 Fri 14 Feb 2020 14:48:05 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:36131 Fri 14 Feb 2020 11:25:05 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:50749 Fri 04 Aug 2023 10:45:52 AEST ]]>